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What is the most comfortable position for a patient with a respiratory problem?

A Fowler's

Fowler’s position can provide relief when a customer is having difficulty breathing. When sitting in Fowler’s position, the customer is upright at 90 degrees, allowing the chest to expand as much as possible. Prone (on the abdomen), supine (on the back), and lateral (on the side) are all flat positions, which can make respiratory distress worse.